Due to various issues with drivers for AMD GCN 1.0 architecture, those cards are no longer supported for Cycles rendering
When using add-ons in Blender 2.79 that take advantage of the new data-block pointer properties, the resulting .blend files can’t be opened in earlier versions of Blender. Attempting to open such .blend files in Blender 2.78c and earlier may crash.
Some Interface Themes may need to be reloaded to work properly.
The text color contained in a layout.box() is now defined in User Preferences » Themes » User Interface » Box section
Rig compatibility:
Changes to IK snapping may affect rigs that use non-uniform IK scaling. (rigs created in the 2.78 builds.)
During the 2.78 series: IK snapping was partly broken.
This has been fixed for Blender 2.79
Rigs created in Blender 2.78 may not be compatible with 2.79.
Rigs created in Blender 2.77 may still work.
When using the add-on Rigify, please note:
Compatibility is broken for this release. There’s no guarantee rigs created in previous Blender versions will work correctly.
Rigs created in Blender 2.78 may not be compatible with 2.79.
Rigs created in Blender 2.77 may still work.
Save your work before attempting upgrading your rigs.